Camarines Sur Iacuc Guidelines Catheter Skull Implant In Mice

Policies and Guidelines Vertebrate Animal Research

Sample IACUC protocol to implant MouseMonitor Telemetry

iacuc guidelines catheter skull implant in mice

IACUC Policy 07 Acceptable Methods of Blood Collection. Three principles drive the designs of our mouse and rat catheters: (1) that each model is designed specifically for the species and vessel; (2) that the catheter has an ideal fit with the external device to which it will be attached; and (3) that customization is simple enough that every surgeon can have a design to match his or her technique., Finally, catheters designed specifically for mice. Each catheter has been customized for a specific access target and tailored to animal size. They are constructed of the same high quality polyurethane used for human applications and are modified by length and bead location to ensure optimal tip placement.Silicone/Poly.

THE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE

Rodent Irradiation & Bone Marrow Transplant Procedures. mice divided into 3 cages). The researcher will be billed $10 for each cage necessary to satisfy the overcrowding policy. If the PI has more than three incidents in a 30 day period, the violation(s) will be reported to the IACUC. Any exceptions to this policy must have prior IACUC approval, IACUC Policy for Identification and Genotyping Methods in Mice Responsible Official: VP for Research Administration applied to mice between the ages of 8 and 12 days without anesthesia. If clipping of toes is to occur after day 12, it must be justified in the protocol and.

IACUC Administrative Policy P-0015-01: Guidelines for the Genotyping of Mice and Rats . Purpose . The specific genetic identification of genetically engineered animals in a litter is critical to the efficient pursuit of research and in reducing the number of animals involved in a research project. IACUC Policy on Euthanasia by Cervical Dislocation or Decapitation . Background The IACUC is specifically charged with reviewing the methods of euthanasia for each research protocol to assure compliance with the recommendations contained in the AVMA Guidelines on Euthanasia. Since physical methods of euthanasia require the most

Jan 04, 2018 · Jackson Laboratory "Genetic Background: understanding its importance in mouse-based biomedical research" Last Review Date: January 4, 2018. This mouse genetics resource manual outlines The Jackson Laboratory's Genetic Quality Control Program for preventing genetic contamination and its Genetic Stability Program for s lowing genetic drift.Additionally, it discusses the importance of UNC-IACUC “First do no harm” – Greek Hippocratic Oath, Great Watch Words of Medicine Basic Information about working with Rats Proper Personal Protection Equipment (PPE) is a requirement for working with animals. In DCM facilities, minimum requirements include disposable coveralls, shoe covers, head bonnet, mask, and gloves.

Jul 25, 2019 · Guideline #21 Exempt Animal Use Activities. 1. Reference: Title 9, Code of Federal Regulations, Subchapter A – Animal Welfare, Parts 1-3 2. Policy: 2.1. Field Studies: Research and/or teaching field studies are exempted from filing an animal care and use protocol (ACUP) and obtaining IACUC approval provided that the field studies are only observational in nature and do not involve … Rodent Colony Management IACUC Policy . 312.1 Mouse Colony Management 312.1.1 Definitions i. Adult Mouse: Any mouse that is of weaning age or older and able to eat solid food and reach the water source. ii. Mouse Pup: Any neonatal or young mouse up to 24 days of age, i.e. standard weaning age. iii.

Whole Animal Perfusion Fixation for Rodents. Gregory J. Gage 1, Daryl R. Kipke 1, William Shain 2. Make a midline incision along the integument from the neck to the nose and expose the skull. The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice. Rodent Irradiation & Bone Marrow Transplant Procedures (LabAn SOP 1) The procedures described in this SOP have been reviewed and approved by the IACUC. If you intend to irradiate mice according to the procedure described in this SOP, • You must state, in your IACUC protocol, your intention to …

Whole Animal Perfusion Fixation for Rodents. Gregory J. Gage 1, Daryl R. Kipke 1, William Shain 2. Make a midline incision along the integument from the neck to the nose and expose the skull. The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice. Tumor Policy for Mice and Rats. Print. On this page: Boston University IACUC Policy on Tumor Guidelines for Rats and Mice; NCI Frederick ACUC Guidelines Involving Experimental Neoplasia Proposals in Mice and Rats, 2006. Wallace, J. (2000). Humane Endpoints and Cancer Research. ILAR 41(2).

Ascites Production in Mice, 01/23/19 ARCHIVED Xenopus laevis Egg and Oocyte Harvesting , 02/27/19 REVISED Pain and Distress in Laboratory Animals: Responsibilities, Recognition and Alleviation , … Rodent Colony Management IACUC Policy . 312.1 Mouse Colony Management 312.1.1 Definitions i. Adult Mouse: Any mouse that is of weaning age or older and able to eat solid food and reach the water source. ii. Mouse Pup: Any neonatal or young mouse up to 24 days of age, i.e. standard weaning age. iii.

RODENT TUMOR AND CANCER MODELS 2 burden experiments. Weight loss is a less desirable criterion because tumor mass may increase more rapidly than cachexia occurs in the patient, leading to a falsely optimistic assessment of the animal’s IACUC Policy on Euthanasia by Cervical Dislocation or Decapitation . Background The IACUC is specifically charged with reviewing the methods of euthanasia for each research protocol to assure compliance with the recommendations contained in the AVMA Guidelines on Euthanasia. Since physical methods of euthanasia require the most

Jan 04, 2018 · Jackson Laboratory "Genetic Background: understanding its importance in mouse-based biomedical research" Last Review Date: January 4, 2018. This mouse genetics resource manual outlines The Jackson Laboratory's Genetic Quality Control Program for preventing genetic contamination and its Genetic Stability Program for s lowing genetic drift.Additionally, it discusses the importance of Find guidelines for mouse anesthesia, including anesthetic drugs and procedures and special considerations for neonatal mouse anesthesia.. Research Animal Resources (RAR) veterinary staff designed these guidelines to be general recommendations, not an inclusive list of all possible drug combinations that can be used in mice.

IACUC Policy 07: Acceptable Methods of Blood Collection . Policy Purpose: 1) To assist investigators and the IACUC members in their choice and application of survival and non -survival rodent bleeding techniques during protocol formulation and review. 2) To Find guidance on administering substances to laboratory animals: Guidelines for injection/administration of substances by siteRecommended locations and approximate needle sizesProcedures must have prior approval from the Institutional Animal Care and Use Committee (IACUC). The approved protocol specific to each study should list the route of administration, intervals between substance

UCSF IACUC Guidelines for Rodent Anesthesia . Using a catheter, pumps may be used to deliver directly into the venous or arterial system. The following procedure details the placement of the catheter in the external jugular vein and requires the attachment of the catheter to the pump. THE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE Sample IACUC Protocol Evaluation of compound effects on EAE development in C57BL/6 mice Introduction and use permissions This document is offered as a sample IACUC protocol. Your institutional IACUC committee may require changes or additions to this …

Three principles drive the designs of our mouse and rat catheters: (1) that each model is designed specifically for the species and vessel; (2) that the catheter has an ideal fit with the external device to which it will be attached; and (3) that customization is simple enough that every surgeon can have a design to match his or her technique. Find guidance on administering substances to laboratory animals: Guidelines for injection/administration of substances by siteRecommended locations and approximate needle sizesProcedures must have prior approval from the Institutional Animal Care and Use Committee (IACUC). The approved protocol specific to each study should list the route of administration, intervals between substance

Finally, catheters designed specifically for mice. Each catheter has been customized for a specific access target and tailored to animal size. They are constructed of the same high quality polyurethane used for human applications and are modified by length and bead location to ensure optimal tip placement.Silicone/Poly Jul 25, 2019 · Guideline #21 Exempt Animal Use Activities. 1. Reference: Title 9, Code of Federal Regulations, Subchapter A – Animal Welfare, Parts 1-3 2. Policy: 2.1. Field Studies: Research and/or teaching field studies are exempted from filing an animal care and use protocol (ACUP) and obtaining IACUC approval provided that the field studies are only observational in nature and do not involve …

IACUC GUIDANCE ON PI RECORDKEEPING FOR ANIMAL RESEARCH INTRODUCTION This document is provided to assist the animal investigator in determining the appropriate and necessary record-keeping for animals in research, as mandated by federal and university laws, regulations, and policies. Find guidance on administering substances to laboratory animals: Guidelines for injection/administration of substances by siteRecommended locations and approximate needle sizesProcedures must have prior approval from the Institutional Animal Care and Use Committee (IACUC). The approved protocol specific to each study should list the route of administration, intervals between substance

It is the responsibility of the Institutional Animal Care and Use Committee (IACUC) to assure that investigators and staff are following this SOP. Surgery to implant a cannula can also be done by the lab, as written and approved Guidelines for Survival Bleeding of … catheter into the artery, till the silicon ring reaches the V-shaped hole. • To be sure that the catheter is not pushed out, the inserted part of catheter can be held in place with the vessel stretcher while the catheter is pushed further using an anatomical forceps. • Tie the second half of the square knot.

Jan 04, 2018 · Jackson Laboratory "Genetic Background: understanding its importance in mouse-based biomedical research" Last Review Date: January 4, 2018. This mouse genetics resource manual outlines The Jackson Laboratory's Genetic Quality Control Program for preventing genetic contamination and its Genetic Stability Program for s lowing genetic drift.Additionally, it discusses the importance of Jan 04, 2018 · Jackson Laboratory "Genetic Background: understanding its importance in mouse-based biomedical research" Last Review Date: January 4, 2018. This mouse genetics resource manual outlines The Jackson Laboratory's Genetic Quality Control Program for preventing genetic contamination and its Genetic Stability Program for s lowing genetic drift.Additionally, it discusses the importance of

The non-dominant hand can drop the forceps to help stabilize the position of the catheter and syringe as the dominant hand is used to slowly inject the inoculum (at least 5 seconds). If fluid is seen flowing around the catheter during injection, either the bladder is full or the catheter … Find guidance on administering substances to laboratory animals: Guidelines for injection/administration of substances by siteRecommended locations and approximate needle sizesProcedures must have prior approval from the Institutional Animal Care and Use Committee (IACUC). The approved protocol specific to each study should list the route of administration, intervals between substance

Common Technical Procedures 1 – An appropriate gavage needle will be selected for species and size of animal using “Rodent Oral Gavage Needle Guidelines” on UGA IACUC website. 2 – The needle will be measured for proper length from mouth to the last rib and marked accordingly. (3mm for small amount of blood, 4mm for mice < 2 Three principles drive the designs of our mouse and rat catheters: (1) that each model is designed specifically for the species and vessel; (2) that the catheter has an ideal fit with the external device to which it will be attached; and (3) that customization is simple enough that every surgeon can have a design to match his or her technique.

Submental Blood Collection in Mice Survival Survival Surgery for the Production of Genetically Modified Mice Lateral Tail Vein Injection in Mice and Rats (Preferred Technique For Vascular Access in Mice) UNC-IACUC “First do no harm” – Greek Hippocratic Oath, Great Watch Words of Medicine Basic Information about working with Rats Proper Personal Protection Equipment (PPE) is a requirement for working with animals. In DCM facilities, minimum requirements include disposable coveralls, shoe covers, head bonnet, mask, and gloves.

IACUC Administrative Policy P-0015-01: Guidelines for the Genotyping of Mice and Rats . Purpose . The specific genetic identification of genetically engineered animals in a litter is critical to the efficient pursuit of research and in reducing the number of animals involved in a research project. IACUC GUIDANCE ON PI RECORDKEEPING FOR ANIMAL RESEARCH INTRODUCTION This document is provided to assist the animal investigator in determining the appropriate and necessary record-keeping for animals in research, as mandated by federal and university laws, regulations, and policies.

Jan 04, 2018 · Survival surgery is defined as any surgical procedure from which the animal will recover, even if only for short periods of time. As with any activity involving animals, the individual(s) carrying out the procedure(s) must be adequately qualified and trained … Common Technical Procedures 1 – An appropriate gavage needle will be selected for species and size of animal using “Rodent Oral Gavage Needle Guidelines” on UGA IACUC website. 2 – The needle will be measured for proper length from mouth to the last rib and marked accordingly. (3mm for small amount of blood, 4mm for mice < 2

Survival Surgery in Rodents & Species Not Regulated by the. IACUC Administrative Policy P-0015-01: Guidelines for the Genotyping of Mice and Rats . Purpose . The specific genetic identification of genetically engineered animals in a litter is critical to the efficient pursuit of research and in reducing the number of animals involved in a research project., Jan 04, 2018 · Jackson Laboratory "Genetic Background: understanding its importance in mouse-based biomedical research" Last Review Date: January 4, 2018. This mouse genetics resource manual outlines The Jackson Laboratory's Genetic Quality Control Program for preventing genetic contamination and its Genetic Stability Program for s lowing genetic drift.Additionally, it discusses the importance of.

IACUC Policy on Euthanasia by Cervical Dislocation or

iacuc guidelines catheter skull implant in mice

Basic Rat Handling and Technique Workshop UNC-IACUC. Find guidance on administering substances to laboratory animals: Guidelines for injection/administration of substances by siteRecommended locations and approximate needle sizesProcedures must have prior approval from the Institutional Animal Care and Use Committee (IACUC). The approved protocol specific to each study should list the route of administration, intervals between substance, NOTE: This animal protocol was approved by the Institutional Animal Care and Use Committee (IACUC) at The Ohio State University. This procedure can be used on any mouse in which the inner diameter of the carotid artery is large enough to insert the catheter. Use mice that are above 16 g (older than ~2 months). 1. Preparing Mouse for Catheterization.

High Quality Catheters for Mice & Rats Instech Laboratories. Mouse Toe Clipping for Identification Policy#: 09 IACUC Approval Date: 1-22-07 Background: Toe Clipping is a method that involves a numerical scheme in which the first bone of certain toes is removed with a sharp instrument for identification of small rodents., It is the responsibility of the Institutional Animal Care and Use Committee (IACUC) to assure that investigators and staff are following this SOP. Surgery to implant a cannula can also be done by the lab, as written and approved Guidelines for Survival Bleeding of ….

IACUC Routes of Administration Guidelines AHC Research

iacuc guidelines catheter skull implant in mice

Basic Rat Handling and Technique Workshop UNC-IACUC. The federally mandated Institutional Animal Care and Use Committee (IACUC) at KSU is the Animal Care and Use Committee (IACUC). The IACUC is responsible for reviewing and approving protocols. Do not conduct experiments, even pilot studies that are not described in your approved animal protocol. Amend protocols to reflect changes in procedure. https://en.wikipedia.org/wiki/Intrathecal_administration Mouse Toe Clipping for Identification Policy#: 09 IACUC Approval Date: 1-22-07 Background: Toe Clipping is a method that involves a numerical scheme in which the first bone of certain toes is removed with a sharp instrument for identification of small rodents..

iacuc guidelines catheter skull implant in mice

  • When are rats mice birds and fish protected by US
  • Comparative Medicine Group Kansas State University
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  • UNC-IACUC “First do no harm” – Greek Hippocratic Oath, Great Watch Words of Medicine Basic Information about working with Rats Proper Personal Protection Equipment (PPE) is a requirement for working with animals. In DCM facilities, minimum requirements include disposable coveralls, shoe covers, head bonnet, mask, and gloves. The catheter should allow free motion of the animal’s head and neck. 10. Close the incision with wound clips or suture. 11. Recover the animal following the UCSF Rodent Anesthesia guidelines and provide analgesia as described in the approved protocol. For mice: Follow the procedure as detailed for rats with the following exceptions:

    Finally, catheters designed specifically for mice. Each catheter has been customized for a specific access target and tailored to animal size. They are constructed of the same high quality polyurethane used for human applications and are modified by length and bead location to ensure optimal tip placement.Silicone/Poly Mouse Toe Clipping for Identification Policy#: 09 IACUC Approval Date: 1-22-07 Background: Toe Clipping is a method that involves a numerical scheme in which the first bone of certain toes is removed with a sharp instrument for identification of small rodents.

    The catheter should allow free motion of the animal’s head and neck. 10. Close the incision with wound clips or suture. 11. Recover the animal following the UCSF Rodent Anesthesia guidelines and provide analgesia as described in the approved protocol. For mice: Follow the procedure as detailed for rats with the following exceptions: The IACUC and the Office of Animal Resources have provided a set of guidance documents (Policies, Guidelines, and Informational Sheets) for use when planning animal procedures at the University of Iowa. Policy - An exception to an IACUC Policy must be described and justified in the Animal Protocol and approved by the full IACUC at a convened monthly meeting.

    The non-dominant hand can drop the forceps to help stabilize the position of the catheter and syringe as the dominant hand is used to slowly inject the inoculum (at least 5 seconds). If fluid is seen flowing around the catheter during injection, either the bladder is full or the catheter … Find guidance on administering substances to laboratory animals: Guidelines for injection/administration of substances by siteRecommended locations and approximate needle sizesProcedures must have prior approval from the Institutional Animal Care and Use Committee (IACUC). The approved protocol specific to each study should list the route of administration, intervals between substance

    Find guidelines for mouse anesthesia, including anesthetic drugs and procedures and special considerations for neonatal mouse anesthesia.. Research Animal Resources (RAR) veterinary staff designed these guidelines to be general recommendations, not an inclusive list of all possible drug combinations that can be used in mice. IACUC Policy 07: Acceptable Methods of Blood Collection . Policy Purpose: 1) To assist investigators and the IACUC members in their choice and application of survival and non -survival rodent bleeding techniques during protocol formulation and review. 2) To

    NOTE: This animal protocol was approved by the Institutional Animal Care and Use Committee (IACUC) at The Ohio State University. This procedure can be used on any mouse in which the inner diameter of the carotid artery is large enough to insert the catheter. Use mice that are above 16 g (older than ~2 months). 1. Preparing Mouse for Catheterization Whole Animal Perfusion Fixation for Rodents. Gregory J. Gage 1, Daryl R. Kipke 1, William Shain 2. Make a midline incision along the integument from the neck to the nose and expose the skull. The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice.

    catheter into the artery, till the silicon ring reaches the V-shaped hole. • To be sure that the catheter is not pushed out, the inserted part of catheter can be held in place with the vessel stretcher while the catheter is pushed further using an anatomical forceps. • Tie the second half of the square knot. Institutional Animal Care and Use Committee 2017 IACUC Chair: Phil Smith Page 1 of 2 . IACUC Policy 03: Complete Freund’s Adjuvant (CFA) Use . Policy Purpose: The intent of this policy is to describe the use of adjuvants at TTU. Guidelines for preparation and administration should assist to eliminate or minimize complications due to

    catheter into the artery, till the silicon ring reaches the V-shaped hole. • To be sure that the catheter is not pushed out, the inserted part of catheter can be held in place with the vessel stretcher while the catheter is pushed further using an anatomical forceps. • Tie the second half of the square knot. Submental Blood Collection in Mice Survival Survival Surgery for the Production of Genetically Modified Mice Lateral Tail Vein Injection in Mice and Rats (Preferred Technique For Vascular Access in Mice)

    The catheter should allow free motion of the animal’s head and neck. 10. Close the incision with wound clips or suture. 11. Recover the animal following the UCSF Rodent Anesthesia guidelines and provide analgesia as described in the approved protocol. For mice: Follow the procedure as detailed for rats with the following exceptions: Rodent Irradiation & Bone Marrow Transplant Procedures (LabAn SOP 1) The procedures described in this SOP have been reviewed and approved by the IACUC. If you intend to irradiate mice according to the procedure described in this SOP, • You must state, in your IACUC protocol, your intention to …

    iacuc guidelines catheter skull implant in mice

    Common Technical Procedures 1 – An appropriate gavage needle will be selected for species and size of animal using “Rodent Oral Gavage Needle Guidelines” on UGA IACUC website. 2 – The needle will be measured for proper length from mouth to the last rib and marked accordingly. (3mm for small amount of blood, 4mm for mice < 2 IACUC Policy 07: Acceptable Methods of Blood Collection . Policy Purpose: 1) To assist investigators and the IACUC members in their choice and application of survival and non -survival rodent bleeding techniques during protocol formulation and review. 2) To

    Sample IACUC protocol to implant MouseMonitor Telemetry

    iacuc guidelines catheter skull implant in mice

    When are rats mice birds and fish protected by US. a. As a method of identification of small rodents (mice and rats), toe clipping is best performed on neonates 5-7 days of age. Mice (not rats) may be toe-clipped up to 13 days of age. b. Written justification for toe-clipping must be approved by the IACUC before the procedure can be performed. The number of toes that will be clipped per animal, Office of Research Compliance (ORC) Institutional Animal Care and Use Committee (IACUC) Cage Card Requirements-Rodents. FULL POLICY CONTENTS Scope.

    Anesthesia Guidelines Mice AHC Research Services

    IACUC Administrative Policy P-0015-01 Guidelines for the. The federally mandated Institutional Animal Care and Use Committee (IACUC) at KSU is the Animal Care and Use Committee (IACUC). The IACUC is responsible for reviewing and approving protocols. Do not conduct experiments, even pilot studies that are not described in your approved animal protocol. Amend protocols to reflect changes in procedure., UCSF IACUC Guidelines for Rodent Anesthesia . Using a catheter, pumps may be used to deliver directly into the venous or arterial system. The following procedure details the placement of the catheter in the external jugular vein and requires the attachment of the catheter to the pump. THE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE.

    IACUC University of Rhode Island MOUSE BREEDING AND CAGE DENSITY POLICY Office of Research Integrity 3 October 2014 Weaning may be delayed for pups unable to eat solid food or … Common Surgical Procedures in Rodents P. L. Foley Office of Animal Research Education and Compliance, University of Virginia, Charlottesville, VA, When the differences in technique for mice are significant, such as catheter sizes, these are discussed within …

    The IACUC and the Office of Animal Resources have provided a set of guidance documents (Policies, Guidelines, and Informational Sheets) for use when planning animal procedures at the University of Iowa. Policy - An exception to an IACUC Policy must be described and justified in the Animal Protocol and approved by the full IACUC at a convened monthly meeting. Submitting an IACUC Protocol, Amendment, or Annual Continuation. InfoEd - All animal use protocols, amendments, administrative changes and annual continuations must be submitted within InfoEd. InfoEd Knowledge Center - For instructions on how to submit or address reviewer comments, please visit the Laboratory Animal Module section of the infoEd Knowldege Center.

    Submental Blood Collection in Mice Survival Survival Surgery for the Production of Genetically Modified Mice Lateral Tail Vein Injection in Mice and Rats (Preferred Technique For Vascular Access in Mice) The IACUC and the Office of Animal Resources have provided a set of guidance documents (Policies, Guidelines, and Informational Sheets) for use when planning animal procedures at the University of Iowa. Policy - An exception to an IACUC Policy must be described and justified in the Animal Protocol and approved by the full IACUC at a convened monthly meeting.

    IACUC Policy for Identification and Genotyping Methods in Mice Responsible Official: VP for Research Administration applied to mice between the ages of 8 and 12 days without anesthesia. If clipping of toes is to occur after day 12, it must be justified in the protocol and The catheter should allow free motion of the animal’s head and neck. 10. Close the incision with wound clips or suture. 11. Recover the animal following the UCSF Rodent Anesthesia guidelines and provide analgesia as described in the approved protocol. For mice: Follow the procedure as detailed for rats with the following exceptions:

    UNC-IACUC “First do no harm” – Greek Hippocratic Oath, Great Watch Words of Medicine Basic Information about working with Rats Proper Personal Protection Equipment (PPE) is a requirement for working with animals. In DCM facilities, minimum requirements include disposable coveralls, shoe covers, head bonnet, mask, and gloves. Sample IACUC protocol to implant MouseMonitor Telemetry radio-telemetry ECG, Temperature-Activity monitor in a mouse MouseMonitor Telemetry radio-telemetry device (1.9 cc, 2.7g) is implanted in the peritoneal cavity of the mouse for the purpose of monitoring ECG, Heart rate, Temperature, and Activity.

    UNC-IACUC “First do no harm” – Greek Hippocratic Oath, Great Watch Words of Medicine Basic Information about working with Rats Proper Personal Protection Equipment (PPE) is a requirement for working with animals. In DCM facilities, minimum requirements include disposable coveralls, shoe covers, head bonnet, mask, and gloves. Submental Blood Collection in Mice Survival Survival Surgery for the Production of Genetically Modified Mice Lateral Tail Vein Injection in Mice and Rats (Preferred Technique For Vascular Access in Mice)

    Mouse Toe Clipping for Identification Policy#: 09 IACUC Approval Date: 1-22-07 Background: Toe Clipping is a method that involves a numerical scheme in which the first bone of certain toes is removed with a sharp instrument for identification of small rodents. IACUC University of Rhode Island MOUSE BREEDING AND CAGE DENSITY POLICY Office of Research Integrity 3 October 2014 Weaning may be delayed for pups unable to eat solid food or …

    Find guidance on administering substances to laboratory animals: Guidelines for injection/administration of substances by siteRecommended locations and approximate needle sizesProcedures must have prior approval from the Institutional Animal Care and Use Committee (IACUC). The approved protocol specific to each study should list the route of administration, intervals between substance Find guidelines for mouse anesthesia, including anesthetic drugs and procedures and special considerations for neonatal mouse anesthesia.. Research Animal Resources (RAR) veterinary staff designed these guidelines to be general recommendations, not an inclusive list of all possible drug combinations that can be used in mice.

    Environmental Enrichment. To provide for the physical and social needs of research animals, the IACUC requires that appropriate environmental enrichment be provided as part of standard animal housing unless there is scientific justification, approved by the IACUC that precludes the use of environmental enrichment materials or practices. The catheter should allow free motion of the animal’s head and neck. 10. Close the incision with wound clips or suture. 11. Recover the animal following the UCSF Rodent Anesthesia guidelines and provide analgesia as described in the approved protocol. For mice: Follow the procedure as detailed for rats with the following exceptions:

    The federally mandated Institutional Animal Care and Use Committee (IACUC) at KSU is the Animal Care and Use Committee (IACUC). The IACUC is responsible for reviewing and approving protocols. Do not conduct experiments, even pilot studies that are not described in your approved animal protocol. Amend protocols to reflect changes in procedure. Institutional Animal Care and Use Committee 2017 IACUC Chair: Phil Smith Page 1 of 2 . IACUC Policy 03: Complete Freund’s Adjuvant (CFA) Use . Policy Purpose: The intent of this policy is to describe the use of adjuvants at TTU. Guidelines for preparation and administration should assist to eliminate or minimize complications due to

    Sample IACUC Protocol Evaluation of compound effects on EAE development in C57BL/6 mice Introduction and use permissions This document is offered as a sample IACUC protocol. Your institutional IACUC committee may require changes or additions to this … IACUC GUIDANCE ON PI RECORDKEEPING FOR ANIMAL RESEARCH INTRODUCTION This document is provided to assist the animal investigator in determining the appropriate and necessary record-keeping for animals in research, as mandated by federal and university laws, regulations, and policies.

    Common Surgical Procedures in Rodents P. L. Foley Office of Animal Research Education and Compliance, University of Virginia, Charlottesville, VA, When the differences in technique for mice are significant, such as catheter sizes, these are discussed within … a. As a method of identification of small rodents (mice and rats), toe clipping is best performed on neonates 5-7 days of age. Mice (not rats) may be toe-clipped up to 13 days of age. b. Written justification for toe-clipping must be approved by the IACUC before the procedure can be performed. The number of toes that will be clipped per animal

    The UW-L IACUC has established the following guidelines for mouse breeding and cage density expectations and requires that all Animal Use Protocols follow one of the common breeding schemes below when breeding laboratory mice (Mus musculus). REFERENCE: Guide for the Care and Use of Laboratory Animals, 8th edition, pages 56-57, 75-77, 107. Jul 25, 2019 · Guideline #21 Exempt Animal Use Activities. 1. Reference: Title 9, Code of Federal Regulations, Subchapter A – Animal Welfare, Parts 1-3 2. Policy: 2.1. Field Studies: Research and/or teaching field studies are exempted from filing an animal care and use protocol (ACUP) and obtaining IACUC approval provided that the field studies are only observational in nature and do not involve …

    Sample IACUC protocol to implant MouseMonitor Telemetry radio-telemetry ECG, Temperature-Activity monitor in a mouse MouseMonitor Telemetry radio-telemetry device (1.9 cc, 2.7g) is implanted in the peritoneal cavity of the mouse for the purpose of monitoring ECG, Heart rate, Temperature, and Activity. Amending a protocol to import and breed . knockout mice . Dr. Paulie O’Rourke was elated when a colleague at another university developed a knockout mouse that was important to O’Rourke’s research. She quickly requested that the Import-Export Coordinator at Great Eastern University import for her two breeding pairs of the knockout mice.

    Common Technical Procedures 1 – An appropriate gavage needle will be selected for species and size of animal using “Rodent Oral Gavage Needle Guidelines” on UGA IACUC website. 2 – The needle will be measured for proper length from mouth to the last rib and marked accordingly. (3mm for small amount of blood, 4mm for mice < 2 It is the responsibility of the Institutional Animal Care and Use Committee (IACUC) to assure that investigators and staff are following this SOP. Surgery to implant a cannula can also be done by the lab, as written and approved Guidelines for Survival Bleeding of …

    Office of Research Compliance (ORC) Institutional Animal Care and Use Committee (IACUC) Cage Card Requirements-Rodents. FULL POLICY CONTENTS Scope Amending a protocol to import and breed . knockout mice . Dr. Paulie O’Rourke was elated when a colleague at another university developed a knockout mouse that was important to O’Rourke’s research. She quickly requested that the Import-Export Coordinator at Great Eastern University import for her two breeding pairs of the knockout mice.

    It is the responsibility of the Institutional Animal Care and Use Committee (IACUC) to assure that investigators and staff are following this SOP. Surgery to implant a cannula can also be done by the lab, as written and approved Guidelines for Survival Bleeding of … Sample IACUC Protocol Evaluation of compound effects on EAE development in C57BL/6 mice Introduction and use permissions This document is offered as a sample IACUC protocol. Your institutional IACUC committee may require changes or additions to this …

    Common Surgical Procedures in Rodents P. L. Foley Office of Animal Research Education and Compliance, University of Virginia, Charlottesville, VA, When the differences in technique for mice are significant, such as catheter sizes, these are discussed within … when no other individual identification method is feasible. Please see the WSU IACUC Rodent Toe‐Clipping Policy. IACUC Guidelines Temporary method: 1. An indelible (permanent) marker can be used to write on the tail or hair coat. 2.

    Submental Blood Collection in Mice Survival Survival Surgery for the Production of Genetically Modified Mice Lateral Tail Vein Injection in Mice and Rats (Preferred Technique For Vascular Access in Mice) Mouse Toe Clipping for Identification Policy#: 09 IACUC Approval Date: 1-22-07 Background: Toe Clipping is a method that involves a numerical scheme in which the first bone of certain toes is removed with a sharp instrument for identification of small rodents.

    Jan 04, 2018 · Survival surgery is defined as any surgical procedure from which the animal will recover, even if only for short periods of time. As with any activity involving animals, the individual(s) carrying out the procedure(s) must be adequately qualified and trained … Whole Animal Perfusion Fixation for Rodents. Gregory J. Gage 1, Daryl R. Kipke 1, William Shain 2. Make a midline incision along the integument from the neck to the nose and expose the skull. The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice.

    Comparative Medicine Group Kansas State University

    iacuc guidelines catheter skull implant in mice

    Office of Research Compliance (ORC) Institutional Animal. Submental Blood Collection in Mice Survival Survival Surgery for the Production of Genetically Modified Mice Lateral Tail Vein Injection in Mice and Rats (Preferred Technique For Vascular Access in Mice), Find guidelines for mouse anesthesia, including anesthetic drugs and procedures and special considerations for neonatal mouse anesthesia.. Research Animal Resources (RAR) veterinary staff designed these guidelines to be general recommendations, not an inclusive list of all possible drug combinations that can be used in mice..

    Anesthesia Guidelines Mice AHC Research Services

    iacuc guidelines catheter skull implant in mice

    Rodent Colony Management IACUC Policy. Institutional Animal Care and Use Committee 2017 IACUC Chair: Phil Smith Page 1 of 2 . IACUC Policy 03: Complete Freund’s Adjuvant (CFA) Use . Policy Purpose: The intent of this policy is to describe the use of adjuvants at TTU. Guidelines for preparation and administration should assist to eliminate or minimize complications due to https://en.wikipedia.org/wiki/Central_venous_catheter Three principles drive the designs of our mouse and rat catheters: (1) that each model is designed specifically for the species and vessel; (2) that the catheter has an ideal fit with the external device to which it will be attached; and (3) that customization is simple enough that every surgeon can have a design to match his or her technique..

    iacuc guidelines catheter skull implant in mice


    Jul 25, 2019 · Guideline #21 Exempt Animal Use Activities. 1. Reference: Title 9, Code of Federal Regulations, Subchapter A – Animal Welfare, Parts 1-3 2. Policy: 2.1. Field Studies: Research and/or teaching field studies are exempted from filing an animal care and use protocol (ACUP) and obtaining IACUC approval provided that the field studies are only observational in nature and do not involve … Rodent Irradiation & Bone Marrow Transplant Procedures (LabAn SOP 1) The procedures described in this SOP have been reviewed and approved by the IACUC. If you intend to irradiate mice according to the procedure described in this SOP, • You must state, in your IACUC protocol, your intention to …

    IACUC Policy 07: Acceptable Methods of Blood Collection . Policy Purpose: 1) To assist investigators and the IACUC members in their choice and application of survival and non -survival rodent bleeding techniques during protocol formulation and review. 2) To Environmental Enrichment. To provide for the physical and social needs of research animals, the IACUC requires that appropriate environmental enrichment be provided as part of standard animal housing unless there is scientific justification, approved by the IACUC that precludes the use of environmental enrichment materials or practices.

    Tumor Policy for Mice and Rats. Print. On this page: Boston University IACUC Policy on Tumor Guidelines for Rats and Mice; NCI Frederick ACUC Guidelines Involving Experimental Neoplasia Proposals in Mice and Rats, 2006. Wallace, J. (2000). Humane Endpoints and Cancer Research. ILAR 41(2). Imaging studies that use rodents sometimes involve intraperitoneal administration of pharmacological compounds. To facilitate such studies, the authors developed a simple and easily mastered technique for placing an intraperitoneal catheter in a conscious mouse. This technique eliminates the need to

    UNC-IACUC “First do no harm” – Greek Hippocratic Oath, Great Watch Words of Medicine Basic Information about working with Rats Proper Personal Protection Equipment (PPE) is a requirement for working with animals. In DCM facilities, minimum requirements include disposable coveralls, shoe covers, head bonnet, mask, and gloves. Rodent Colony Management IACUC Policy . 312.1 Mouse Colony Management 312.1.1 Definitions i. Adult Mouse: Any mouse that is of weaning age or older and able to eat solid food and reach the water source. ii. Mouse Pup: Any neonatal or young mouse up to 24 days of age, i.e. standard weaning age. iii.

    It is often convenient as well as less interruptive to the animals to add medication and experimental compounds to the drinking water, rather than administering them by gavage or parenterally. A critical factor to be determined when any compound is added to the drinking water is the animals’ fluid IACUC Administrative Policy P-0015-01: Guidelines for the Genotyping of Mice and Rats . Purpose . The specific genetic identification of genetically engineered animals in a litter is critical to the efficient pursuit of research and in reducing the number of animals involved in a research project.

    IACUC GUIDANCE ON PI RECORDKEEPING FOR ANIMAL RESEARCH INTRODUCTION This document is provided to assist the animal investigator in determining the appropriate and necessary record-keeping for animals in research, as mandated by federal and university laws, regulations, and policies. Office of Research Compliance (ORC) Institutional Animal Care and Use Committee (IACUC) Cage Card Requirements-Rodents. FULL POLICY CONTENTS Scope

    catheter into the artery, till the silicon ring reaches the V-shaped hole. • To be sure that the catheter is not pushed out, the inserted part of catheter can be held in place with the vessel stretcher while the catheter is pushed further using an anatomical forceps. • Tie the second half of the square knot. IACUC Administrative Policy P-0015-01: Guidelines for the Genotyping of Mice and Rats . Purpose . The specific genetic identification of genetically engineered animals in a litter is critical to the efficient pursuit of research and in reducing the number of animals involved in a research project.

    Institutional Animal Care and Use Committee 2017 IACUC Chair: Phil Smith Page 1 of 2 . IACUC Policy 03: Complete Freund’s Adjuvant (CFA) Use . Policy Purpose: The intent of this policy is to describe the use of adjuvants at TTU. Guidelines for preparation and administration should assist to eliminate or minimize complications due to The catheter should allow free motion of the animal’s head and neck. 10. Close the incision with wound clips or suture. 11. Recover the animal following the UCSF Rodent Anesthesia guidelines and provide analgesia as described in the approved protocol. For mice: Follow the procedure as detailed for rats with the following exceptions:

    Find guidance on administering substances to laboratory animals: Guidelines for injection/administration of substances by siteRecommended locations and approximate needle sizesProcedures must have prior approval from the Institutional Animal Care and Use Committee (IACUC). The approved protocol specific to each study should list the route of administration, intervals between substance IACUC Administrative Policy P-0015-01: Guidelines for the Genotyping of Mice and Rats . Purpose . The specific genetic identification of genetically engineered animals in a litter is critical to the efficient pursuit of research and in reducing the number of animals involved in a research project.

    iacuc guidelines catheter skull implant in mice

    Find guidelines for mouse anesthesia, including anesthetic drugs and procedures and special considerations for neonatal mouse anesthesia.. Research Animal Resources (RAR) veterinary staff designed these guidelines to be general recommendations, not an inclusive list of all possible drug combinations that can be used in mice. Common Surgical Procedures in Rodents P. L. Foley Office of Animal Research Education and Compliance, University of Virginia, Charlottesville, VA, When the differences in technique for mice are significant, such as catheter sizes, these are discussed within …

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